Preparation and Evaluation of Intravaginal Ring Containing Drospirenone

Table 3

Thermal parameters obtained by differential thermal scanning calorimetry of drospirenone in silicone elastomer (𝑛=3, mean ± SD).

Drospirenone concentration (%)	Enthalpy of melting; Δ𝐻 (J/g)	Onset temperature (°C)	Peak temperature (°C)
1.0	0.34±0.04	191.50±0.26	193.70±0.20
2.0	0.94±0.07	191.82±0.25	193.80±0.02
5.0	2.52±0.07	192.39±0.43	194.61±0.37
10.0	4.81±0.09	192.35±0.39	194.52±0.59
15.0	7.53±0.20	192.15±0.19	194.47±0.25
20.0	8.83±0.15	192.46±0.23	195.07±0.45