Preparation and Evaluation of Intravaginal Ring Containing Drospirenone

Table 5

The results of API excipients compatibility testing under strong light exposure (4500 LX).

Light exposure	API and excipients
	Drospirenone	Drospirenone + PVPk30	Drospirenone + silicone elastomer
0 d
S (%)	0.03	0.08	0.03
T (%)	0.09	0.16	0.14
5 d
S (%)	0.03	0.14	0.03
T (%)	0.11	0.22	0.17
10 d
S (%)	0.08	0.15	0.03
T (%)	0.16	0.22	0.15

S: single impurities; T: total impurities; API: drospirenone.