Review Article
Phytochemistry, Pharmacology and Toxicology of Spilanthes acmella: A Review
Table 2
Summary of pharmacological actions of Spilanthes acmella.
| SL. no. | Pharmacological activity | Parts of plant used | Experimental models | Animals used | References |
| 1 | Local anaesthetic | Whole plant | Intracutaneous wheal in guinea pigs and plexus anaesthesia in frog | Guinea pig, frog | [19] | 2 | Antipyretic activity | Whole plant | Yeast induced pyrexia | Albino rats | [19] | 3 | Anti-inflammatory activity | Whole plant, leaves | Carrageenan induced paw oedema | Albino rats | [22, 31] | 4 | Analgesic activity | Whole plant | Tail flick method, acetic acid induced abdominal constriction | Albino rats | [22] | 5 | Antifungal activity | Flowers | — | — | [23] | 6 | Diuretic activity | Flowers (cold water extract), whole plant | Induction of dieresis using cold water extract | Albino rats | [24, 25] | 7 | Vasorelaxant activity | Flowers | Partially endothelium induced nitric oxide and PGI2 | Albino rats | [30, 31] | 8 | Antioxidant activity | Leaves & whole plant | DPPH Assay, TBARs and SOD method | Invitro, no animal | [30, 31] | 9 | Pancreatic lipase inhibition | Flowers | — | Invitro, no animal | [29] | 10 | Antimalarial & larvicidal activity | Spilanthol extracted from whole plant | — | Eggs & pupae of vector | [37] | 11 | Aphrodisiac activity | Whole plant | — | Male rats | [1] | 12 | Antinociceptive activity | Whole plant | Acetic acid induced writhing | Mice | [31] | 13 | Immunomodulatory activity | Whole plant | — | Rats | [36] | 14 | Bioinsecticidal | Whole plant, leaves | — | — | [2, 12, 32] | 15 | Convulsant | Whole plant | Electroencephalogram (EEG) analysis | Albino rat | [25] |
|
|