Antioxidant Potential of a Polyherbal Antimalarial as an Indicator of Its Therapeutic Value

Table 4

Effect of Nefang on oxidative stress markers in CCl₄-treated wistar rats.

Biochemical parameters	Group A; (corn oil)	Group B; ( CCl4)	Group C; (CCl4 + 100 mg/kg Nefang)	Group D; (CCl4 + 500 mg/kg Nefang)
SOD (UI/mg)	8.15 ± 0.35	6.77 ± 0.19*	8.54 ± 0.53	9.56 ± 0.43^#
CAT (UI/mg)	0.1 ± 0.20	0.04 ± 0.00**	0.14 ± 0.04^#	0.12 ± 0.30^#
MDA (µMol/L)	1.15 ± 0.30	1.18 ± 0.19*	1.17 ± 0.07	1.07 ± 0.05^#
TP (mg/mL)	24.05 ± 1.06	27.72 ± 1.06*	20.51 ± 1.53^#	24.15 ± 2.8

SOD: superoxide dismutase, CAT: catalase, MDA: malondialdehyde, TP: total proteins.Results presented as mean ± SD; 𝑛=5; significant difference: compared to normal control—*𝑃<0.05, **𝑃<0.01, compared to untreated control—^#𝑃<0.05, ^##𝑃<0.01.