718313.fig.001a
(a) Thoracic Aorta
718313.fig.001b
(b) Thoracic Aorta
718313.fig.001c
(c) Abdominal Aorta
718313.fig.001d
(d) Abdominal Aorta
Figure 1: The panel compares the concentration-inhibition response curves (CRC) to acetylcholine (ACh) determined in phenylephrine (PE—1 μM)-constricted thoracic ((a) and (b) panels) and abdominal ((c) and (d) panels) aortic rings with intact endothelium either in the presence or absence of cyclosporine (CsA—1 mg/mL) or tacrolimus (Tac—0.1 mg/mL) maintained in the incubation medium for a period of 30 min after isolation from 13-week-old male Sprague Dawley rats ( ). * and ** compared to respective data in the control group.