Comparative In Vitro Effects of Calcineurin Inhibitors on Functional Vascular Relaxations of Both Rat Thoracic and Abdominal Aorta
Figure 2
The panel compares the CRC to sodium nitroprusside (SNP) determined in PE (1 μM)-constricted thoracic ((a) and (b) panels) and abdominal ((c) and (d) panels) aortic rings in the presence or absence of cyclosporine (CsA—1 mg/mL) and tacrolimus (Tac—0.1 mg/mL). Each data point is mean ± SEM value obtained from aortic rings isolated from 6 rats.