Table 1: Percentage inhibition of xylene-induced ear edema by curcuminoids, turmerones, and COFAE.

TreatmentInhibition (%)

Vehicle control0
Dexamethasone (0.5 mg/kg)58.9
Diclofenac (50 mg/kg)66.6
Curcuminoids (20 mg/kg)64.1
Curcuminoids (60 mg/kg)76.9
Curcuminoids (180 mg/kg)53.8
Turmerones (0.05 mL/kg)66.6
Turmerones (0.1 mL/kg)61.5
Turmerones (0.25 mL/kg)38.4
COFAE (90 mg/kg)51.2
COFAE (180 mg/kg)35.8
COFAE (360 mg/kg)48.7