Antihyperglycemic Activity of Houttuynia cordata Thunb. in Streptozotocin-Induced Diabetic Rats

Table 1

Effect of HC on FPG in streptozotocin-induced diabetic rats.

Group (𝑛=3)	Treatment (dose in mg/kg)	Fasting plasma glucose concentration (mg/dL)
		1st day	7th day	14th day	21st day
I	NC	85.62±3.8	83.01±3.05	85.40±3.63	80.10±2.92
II	DC	294.72±11.07^a	319.72±12.41^a	362.99±13.63^a	365.15±13.29^a
III	Glib (10)	327.67±10.7^a	184.91±6.72^a,b	152.63±4.67^a,b	122.62±3.87^b
IV	HC (100)	271.48±18.87^a	293.77±16.11^a,c	320.52±20.89^a,c	324.64±15.33^a,c
V	HC (200)	275.07±14.42^a	322.25±12.68^a,c	260.82±12.95^a,b,c,d	190.50±11.36^a,b,c,d
VI	HC (400)	316.20±15.87^a	299.68±14.57^a,c	208.56±11.56^a,b,c,d,	146.86±8.26^a,b,d,e

Results are expressed as mean ± SEM, 𝑛=6, ^a𝑃<0.05 compared to normal control; ^b𝑃<0.05 compared to diabetic control; ^c𝑃<0.05 compared to glibenclamide; ^d𝑃<0.05 compared to HC 100; ^e𝑃<0.05 compared to HC 200 (two-way ANOVA followed by Bonferroni posttest).