Table 2: Summary of the stability of cefuroxime in human plasma on different conditions .

Stability conditionsConcentration ( g/mL)Calculated concentration
Mean ± SD ( g/mL)Accuracy%RSD%

Short-term (6 h, 25°C)0.0842 94.972.75
1.68 100.81.47
16.8 97.630.40

Long-term (145 days, −20°C)0.105 98.264.22
1.68 103.02.25
16.8 99.942.36

Autosampler (20 h, 4°C)0.0842 97.763.89
1.68 101.81.47
16.8 98.791.63

Three freeze-thaw cycles (from 25°C to −20°C)0.0842 99.465.76
1.68 102.11.84
16.8 98.652.15