Research Article
Antileishmanial Effect of 5,3′-Hydroxy-7,4′-dimethoxyflavanone of Picramnia gracilis Tul. (Picramniaceae) Fruit: In Vitro and In Vivo Studies
Table 1
In vitro cytotoxicity and antileishmanial activity of Picramnia gracilis Tul.
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Data represent the mean value ± SD of cytotoxicity in terms of 50% lethal concentration (LC50) and leishmanicidal activity in terms of 50% effective concentration (EC50). E-EtOH-fr: ethanolic extract from fruit; E-EtOH-le: ethanolic extract from leaves; E-DiClMe-le: dichloromethane extract from leaves; E-He-le: hexane extract from leaves; and E-EtAc-le: ethyl acetate extract from leaves. IS (index of selectivity) = LC50/EC50. |