Research Article
Antileishmanial Effect of 5,3′-Hydroxy-7,4′-dimethoxyflavanone of Picramnia gracilis Tul. (Picramniaceae) Fruit: In Vitro and In Vivo Studies
Table 2
Blood levels of ALT, BUN, and creatinine in hamsters treated with 5,3′-hydroxy-7,4′-dimethoxyflavanone.
| Group | ALT (U/L) | BUN (mg/dL) | Creatinine (mg/dL) |
| (A) TD0 | | | | Healthy () |
64.4 ± 5.6 | 15.9 ± 2.6 | 0.4 ± 0.1 | Infected/untreated () | 73.9 ± 2.8 | 18.2 ± 1.9 | 0.4 ± 0.14 | Flavanone solution () | 67.8 ± 3.2 | 18.0 ± 4.9 | 0.5 ± 0.1 | Flavanone cream () | 65.8 ± 17.6 | 17.4 ± 1.3 | 0.3 ± 0.02 | MA (i.l) () | 57.0 ± 6.1 | 20.9 ± 6.9 | 0.4 ± 0.1 | (B) TD8 | | | | Flavanone solution () | 76.8 ± 3.7 | 20.0 ± 2.2 | 0.4 ± 0.03 | Flavanone cream () | 77.1 ± 7.6 | 22.9 ± 6.4 | 0.3 ± 0.1 | MA (i.l) () | 62.0 ± 8.5 | 23.8 ± 2.2 | 0.8 ± 0.1 |
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Data represent the mean values ± SD of animals per group of treatment.
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