Effects of Curcumin on Parameters of Myocardial Oxidative Stress and of Mitochondrial Glutathione Turnover in Reoxygenation after 60 Minutes of Hypoxia in Isolated Perfused Working Guinea Pig Hearts

Table 1

Cardiac parameters.

	Normoxia	Hypoxia 60 min	Reoxygenation
Systolic pressure: cm H2O (; mean ± SD)
	94.61 ± 9.38	0	52.31 ± 6.12 (55.3%)
Curc. 0.25 µM	92.73 ± 10.06	0	83.37 ± 7.96 (89.9%)
Curc. 0.5 µM	95.12 ± 11.0	0	77.78 ± 10.24 (83.2%)
Normoxia (mean = 94.15 = 100%)			73.2%
Curc. 0.25 µM			85.6%
Curc. 0.5 µM			88.1%
Aortic flow: mL × min^−1 (; mean ± SD)
	14.13 ± 4.70	0	4.37 ± 3.85 (30.9%)
Curc. 0.25 µM	12.20 ± 3.75	0	6.10 ± 3.34 (50.0%)
Curc. 0.5 µM	14.27 ± 4.73	0	6.73 ± 4.33 (47.2%)
Normoxia (mean = 13.5 = 100%)			32.4%
Curc. 0.25 µM			45.2%
Curc. 0.5 µM			49.9%
Coronary flow: mL × min^−1 (; mean ± SD)
	9.53 ± 3.04	0	15.97 ± 7.39 (167.6%)
Curc. 0.25 µM	10.53 ± 2.5	0	13.6 ± 3.56 (129.2%)
Curc. 0.5 µM	8.9 ± 6.48	0	13.27 ± 7.19 (149.1%)
Normoxia (mean = 9.65 = 100%)			165.5%
Curc. 0.25 µM			140.9%
Curc. 0.5 µM			137.5%