Anti-Parkinson Activity of Petroleum Ether Extract of Ficus religiosa (L.) Leaves
Table 2
Effect of PEFRE on the levels of lipid peroxidation (MDA), catalase (CAT), superoxide dismutase (SOD), and reduced glutathione (GSH) in the brain of 6-OHDA treated animals.
Group
MDA (nM/mg of protein)
CAT (μmoles of H2O2 used/min/mg protein)
SOD (units/mg protein)
GSH (nM/mg of protein)
Vehicle control
1.311 ± 0.09315
5.788 ± 0.046
3.185 ± 0.1852
4.371 ± 0.07576
6-OHDA control
2.616 ± 0.1602#
3.463 ± 0.035#
2.06 ± 0.1068#
3.985 ± 0.020#
Levodopa
1.659 ± 0.03551
6.525 ± 0.20
9.667 ± 0.8333
7.023 ± 0.6013
PEFRE (100)
2 ± 0.1558
3.544 ± 0.15
2.419 ± 0.8732
4.182 ± 0.01312
PEFRE (200)
1.975 ± 0.2153
4.234 ± 0.11
2.801 ± 0.5034
4.614 ± 0.1312
PEFRE (400)
1.347 ± 0.2501
6.22 ± 0.31
8.833 ± 0.8333
8.455 ± 0.03936
Values are expressed as mean ± SEM. , , and as compared to 6-OHDA treated control group (Group II) Groups III to VI were compared with Group II, as compared to vehicle treated group (Group I) Group II was compared with Group I.
