Antidiabetic Effects of the Ethanolic Root Extract of Uvaria chamae P. Beauv (Annonaceae) in Alloxan-Induced Diabetic Rats: A Potential Alternative Treatment for Diabetes Mellitus
Table 2
Effect of the root extract of U. chamae on lipids (mg/dl) in alloxan-induced diabetes mellitus.
Parameters
Control (2% acacia)
Glibenclamide (71 µg/kg)
Pioglitazone (429 µg/kg)
UC (100 mg/kg)
UC (250 mg/kg)
UC (400 mg/kg)
Diabetic untreated
TChol
151.3 ± 4.67
168.7 ± 17.4
172.3 ± 13.0
176.0 ± 5.0
163.0 ± 13.8
163.0 ± 1.8
179.3 ± 11.1
TG
51.33 ± 9.40
53.3 ± 6.8
57.7 ± 7.80
55.3 ± 5.90
43.3 ± 3.80
46.0 ± 5.03
65.7 ± 0.33
HDL
35.33 ± 0.88
47.33 ± 4.97
41.67 ± 4.97
44.67 ± 2.4
50.0 ± 2.88
57.67 ± 1.5
33.67 ± 3.18
LDL
105.7 ± 0.60
110.7 ± 1.3
119.1 ± 1.03
120.3 ± 0.52
104.3 ± 0.12
96.1 ± 0.30
132.2 ± 0.30
Significant difference (;) between the mean ± SEM of test groups vs. control. UC: Uvaria chamae.
