| Assay | Organism tested | Dose/concentration | Molecular targets | References |
| LPS-induced mouse mastitis | Mouse mastitis | 10, 25, and 50 mg/kg | TNF-α↓, IL-1β↓, IL-6↓, p65┴, and IκBα┴ | [92] | LPS-induced endotoxemia and lung injury in mice | Mice (lung) | 25, 50, and 75 mg/kg | TNF-α┴, IL-1β┴, and IL-6┴ | [122] | LPS-induced macrophages in mice | Mouse cells | 1–100 µg/mL | iNOS↓, COX-2↓,TNF-α↓, IL-1β↓, IL-6↓, MIP-1α↓, MCP-1↓, NF-κB p65┴, IκBα┴, and NO┴ | [127] | LPS-induced RAW 264.7 cells. | Mice (RAW 264.7 cells) | 1, 10, and 100 M | NO↓ and TNF-α↓ | [37] | Inhibitory activity on the histamine release by KU812 cells | KU812 cells | 10 to 30 mol/L | IL-4↓, IL-13↓, and (IFN-γ) no effect | [12] | LPS-induced inflammation in RAW 264.7 cells | Mice (RAW 264.7 cells) | | NO┴, IL-6┴, and PGE2┴ | [33] | P. gingivalis-induced human gingival epithelial (HGE) cells | Human gingival epithelial cells | | COX-2┴, IL-6┴, IL-8┴, MMP-1┴, MMP-3┴, PGE-2┴, and IL-4┴ | [125] | Anti-inflammatory effects on Leptospira interrogans-induced inflammatory response | Uterine and endometrial epithelial cells of mice | 100 g/mL | TNF-α┴, IL-1β┴, IL-6┴, NF-κB↓, p38┴, p-p38 MAPK↓, ERK┴, JNK┴, and p-p65↓ | [124] | Protective effects against ovalbumin- (OVA-) induced allergic inflammation | Mouse model of allergic asthma | 0.5 mg/kg and 1 mg/kg | SOCS-3┴, SOCS-5┴, and IFN-γ↑ | [126] | Alleviation in hepatic fibrosis function | Diabetic rats and nondiabetic rats | | PAR2┴, IL-1β↓, IL-6↓, TNF-α↓, and TGF-β1┴ | [128] | Prevention from atopic dermatitis | NC/Nga mice | 1.5 mg/kg | IgE↓ | [87] |
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