Comparative Direct Compression Property of a Novel Pregelatinized Starch in Paracetamol Tablets

Table 3

The properties of tablets of PGTBIS containing magnesium stearate (MgS) (0–2%).

^∗MgS (%)	Starch type	Weight (mg)	^∗TBF (N)	^∗TS (MPa)	^∗LSR	Friability (%)	DT (min)
0.00	PGTBIS	301 ± 7	136.3 ± 5.1	2.34 ± 0.07	0.00	0.22 ± 0.01	3.2 ± 0.2
	Starch 1500®	303 ± 14	91.1 ± 4.0	1.44 ± 0.08	0.00	0.47 ± 0.01	6.2 ± 0.2
0.25	PGTBIS	302 ± 5	92.4 ± 4.2	1.54 ± 0.08	0.34	0.39 ± 0.01	4.0 ± 0.0
	Starch 1500®	303 ± 8	63.0 ± 2.6	1.02 ± 0.03	0.29	0.71 ± 0.01	6.6 ± 0.2
0.50	PGTBIS	303 ± 6	75.9 ± 5.2	1.23 ± 0.09	0.47	0.56 ± 0.01	6.2 ± 0.3
	Starch 1500®	303 ± 8	56.8 ± 2.6	0.90 ± 0.04	0.38	1.05 ± 0.01	8.0 ± 0.2
0.75	PGTBIS	302 ± 5	54.8 ± 3.9	0.89 ± 0.07	0.62	1.09 ± 0.04	6.9 ± 0.3
	Starch 1500®	302 ± 4	55.4 ± 2.5	0.87 ± 0.04	0.40	1.20 ± 0.01	8.9 ± 0.2
1.00	PGTBIS	302 ± 4	49.2 ± 3.7	0.80 ± 0.07	0.66	1.12 ± 0.01	7.8 ± 0.4
	Starch 1500®	301 ± 6	49.8 ± 2.2	0.78 ± 0.03	0.46	1.35 ± 0.01	10.0 ± 0.2
1.50	PGTBIS	302 ± 3	33.1 ± 5.9	0.54 ± 0.09	0.77	4.70 ± 0.20	9.6 ± 0.5
	Starch 1500®	302 ± 4	32.9 ± 2.0	0.51 ± 0.03	0.65	5.30 ± 0.01	11.0 ± 0.2
2.00	PGTBIS	299 ± 3	16.6 ± 4.7	0.27 ± 0.08	0.89	8.75 ± 1.20	11.9 ± 0.5
	Starch 1500®	300 ± 4	14.0 ± 1.0	0.22 ± 0.02	0.85	Friable	13.8 ± 0.2

MgS, TBF, TS, and LSR stand for magnesium stearate, tablet-breaking force, tensile strength, and lubricant sensitivity ratio, respectively.