Exploring the Effect of Compound Glycyrrhizin and Silybinin on the Metabolism of Pexidartinib in Rats Based on CYP3A4 and CYP2C9

Figure 2

Representative chromatograms of PXD and ISTD: (a). The blank plasma; (b). The blank plasma adulterated with PXD and ISTD; (c). The specimens were taken from rats after oral dosing of 40 mg/kg PXD for 4.0 h in group B; (d). The specimens were taken from rats after oral dosing of 40 mg/kg PXD for 4.0 h in group C.