Enhancement of Liver Targetability through Statistical Optimization and Surface Modification of Biodegradable Nanocapsules Loaded with Lamivudine

Table 1

Description of the three formulation factors and their levels taken in this work.

Factor	Description	Level
		−1	0	+1
A	Polymer concentration in final weight of nanocapsules (% w/w)	50	62.5	75
B	Surfactant concentration in secondary emulsion (% w/v)	0	0.25	0.5
C	Concentration of glycerol in external phase (% v/v)	0	25	50