In Vivo Antimalarial Activity of Cyperus rotundus and Its Combination with Dihydroartemisinin against Plasmodium berghei

Table 2

Combination index of interaction between DHA and CRE against PbANKA infection in mice.

Antimalarial test		Dose (mg/kg)		CI value
		DHA	CRE
Combination	ED50	2	400	0.92488^a
	ED50/2	1	200	0.21701^a
	ED50/4	0.5	100	1.85871^b
	ED50/8	0.25	50	2.34981^b

^aCI < 1, synergism; ^bCI > 1, antagonism.