Mutational and Bioinformatic Analysis of Haloarchaeal Lipobox-Containing Proteins

Figure 1

Tat and Sec signal peptides containing lipobox motifs. N-terminal regions of the precursors of (a) Tat; and (b) Sec substrates with lipoboxes (bold) predicted by at least two of the three lipoprotein prediction programs (PredLipo, LipoP and Prosite PS51257), with the exception of Hvo_1242, which was only LipoP-positive. Tat motifs (red) were predicted by TatFind, hydrophobic stretches (underlined), and SPase I cleavage sites (italics) were predicted by Phobius. An arrow indicates the predicted SPase II cleavage sites.