Mutational and Bioinformatic Analysis of Haloarchaeal Lipobox-Containing Proteins
Figure 5
Only haloarchaeal Tat substrates are predicted to be predominantly lipoproteins. The predicted relative proportions are shown for several types of secreted proteins for halophilic and non-halophilic euryarchaeal species as well as crenarchaeal species and three species belonging to other archaeal phyla. (a) The percentage of secreted proteins that are Tat substrates. (b) The percentage of secreted proteins that are lipoproteins. (c) The percentage of Tat substrates that are lipoproteins. (d) The percentage of Sec substrates that are lipoproteins. (e) The percentage of lipoproteins that are secreted via the Tat pathway. (f) The percentage of proteins that are secreted (predicted Tat and Sec substrates with SPase I or SPase II cleavae sites). Raw data are available in Supplementary Table . Organisms are abbreviated as follows: haloarchaea (Hamar: Haloarcula marismortui; Hasal: Halobacterium salinarum; Hfvol: Haloferax volcanii; Hqwal: Haloquadratum walsbyi; Namag: Natrialba magadii; Napha: Natronomonas pharaonis), other euryarchaea (Arcfu: Archaeoglobus fulgidus; Mmaze: Methanosarcina mazei; Pyrfu: Pyrococcus furiosus; Thkod: Thermococcus kodakarensis; Methu: Methanospirillum hungatei; Metja: Methanocaldococcus jannaschii; Metka: Methanopyrus kandleri; Picto: Picrophilus torridus; Theac: Thermoplasma acidophilum), crenarchaea (Apern: Aeropyrum pernix; Calma: Caldivirga maquilingensis; Hypbu: Hyperthermus butylicus; Sulac: Sulfolobus acidocaldarius; Sulso: Sulfolobus solfataricus; Thneu: Thermoproteus neutrophilus; Metse: Metallosphaera sedula; Pyrar: Pyrobaculum arsenaticum; Ighos: Ignicoccus hospitalis), and other archaea (Nequi: Nanoarchaeum equitans; Kocry: Korarchaeum cryptofilum; Nitma: Nitrosopumilus maritimus).
