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Archaea
Volume 2010 (2010), Article ID 690737, 16 pages
http://dx.doi.org/10.1155/2010/690737
Research Article

The Genome Sequence of Methanohalophilus mahii SLPT Reveals Differences in the Energy Metabolism among Members of the Methanosarcinaceae Inhabiting Freshwater and Saline Environments

1DSMZ—German Collection of Microorganisms and Cell Cultures GmbH, 38124 Braunschweig, Germany
2DOE Joint Genome Institute, Walnut Creek, CA 94598-1632, USA
3Los Alamos National Laboratory, Bioscience Division, Los Alamos, NM 87545-001, USA
4Biological Data Management and Technology Center, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
5Oak Ridge National Laboratory, Oak Ridge, TN 37830-8026, USA
6HZI—Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany
7Davis Genome Center, University of California, Davis, CA 95817, USA

Received 24 August 2010; Accepted 9 November 2010

Academic Editor: Valérie de Crécy-Lagard

Copyright © 2010 Stefan Spring et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Methanohalophilus mahii is the type species of the genus Methanohalophilus, which currently comprises three distinct species with validly published names. Mhp. mahii represents moderately halophilic methanogenic archaea with a strictly methylotrophic metabolism. The type strain SLPT was isolated from hypersaline sediments collected from the southern arm of Great Salt Lake, Utah. Here we describe the features of this organism, together with the complete genome sequence and annotation. The 2,012,424 bp genome is a single replicon with 2032 protein-coding and 63 RNA genes and part of the Genomic Encyclopedia of Bacteria and Archaea project. A comparison of the reconstructed energy metabolism in the halophilic species Mhp. mahii with other representatives of the Methanosarcinaceae reveals some interesting differences to freshwater species.