More Than 200 Genes Required for Methane Formation from H2 and CO2 and Energy Conservation Are Present in Methanothermobacter marburgensis and Methanothermobacter thermautotrophicus

<table>Enzymes, coenzymes, and prosthetic groups involved in the energy metabolism of Methanothermobacter marburgensis and Methanothermobacter thermautotrophicus during growth on H2 and CO2. For the synthesis of these components, more than 200 coding sequences are required. A stoichiometry of 4 Na+/ATP of the A1A0-ATP synthase AhaA-IK was assumed to yield 0.5 ATP for every methane generated. This is also predicted from the thermodynamics at physiological H2 concentrations. MFR, methanofuran; H4MPT, tetrahydromethanopterin; CHO-MFR, formyl-MFR; CHO-H4MPT, formy-H4MPT; CH ≡ H4MPT+, methenyl-H4MPT+; CH2 = H4MPT, methylene-H4MPT; CH3-H4MPT, methyl-H4MPT; Fd, ferredoxin.</table>

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Figure 2: More Than 200 Genes Required for Methane Formation from H2 and CO2 and Energy Conservation Are Present in Methanothermobacter marburgensis and Methanothermobacter thermautotrophicus

Figure 2 | More Than 200 Genes Required for Methane Formation from H2 and CO2 and Energy Conservation Are Present in Methanothermobacter marburgensis and Methanothermobacter thermautotrophicus 