Synthetic Archaeosome Vaccines Containing Triglycosylarchaeols Can Provide Additive and Long-Lasting Immune Responses That Are Enhanced by Archaetidylserine

<table>Elispot assay showing a relationship between adjuvant activity of glycosylarchaeol/PGP archaeosomes, archaetidylserine (AS), and archaetidylethanolamine (AE). Mol% compositions for OVA-archaeosome vaccines were mannotriosyl-A/gentiotriosyl-A/PGP (22.5/22.5/55), mannotriosyl-A/gentiotriosyl-A/AS/PGP (22.5/22.5/30/25), mannotriosyl-A/gentiotriosyl-A/AE/PGP (22.5/22.5/5/50), mannotriosyl-A/gentiotriosyl-A/AS/AE/PGP (22.5/22.5/30/5/20). Assays were conducted on splenic cells of mice 6 weeks post first immunization.</table>

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Figure 5

Figure 5: Synthetic Archaeosome Vaccines Containing Triglycosylarchaeols Can Provide Additive and Long-Lasting Immune Responses That Are Enhanced by Archaetidylserine 

Figure 5 | Synthetic Archaeosome Vaccines Containing Triglycosylarchaeols Can Provide Additive and Long-Lasting Immune Responses That Are Enhanced by Archaetidylserine 