Research Article

Unique Characteristics of the Pyrrolysine System in the 7th Order of Methanogens: Implications for the Evolution of a Genetic Code Expansion Cassette

Figure 2

Secondary structure of the in the Thermoplasmata-related 7th order. The stem-loop structure of the in the 7th methanogenic order is shown, in comparison with the structure in bacteria (Desulfitobacterium hafniense, left) and in Methanosarcinaceae (Methanosarcina barkeri, right). The name of each region of the tRNA is indicated. The anticodon CUA (corresponding to the amber codon) is outlined in blue. For the two in M. luminyensis, the modified bases in no. 2 compared to no. 1 are written in red. Adapted and updated from [11, 13].
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