Research Article

A Phylogenomic Census of Molecular Functions Identifies Modern Thermophilic Archaea as the Most Ancient Form of Cellular Life

Figure 1

Overview of the phylogenomic methodology. A matrix of raw census of GOTMF terms was normalized, standardized, and rescaled for phylogenetic reconstruction. Trees of functions (ToFs) were polarized by maximum character state (i.e., V) while trees of life were polarized (ToLs) by the minimum value (0) in the matrix.
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