Research Article

Towards a Computational Model of a Methane Producing Archaeum

Table 2

A list of enzyme stoichiometries in the cell mass reaction. The moles of the indicated protein that are created from 1 mole of ATP calculated in Section 2.6.

Enzyme Methanol Acetate
(μmol/mol) (μmol/mol)

Ack 37.5 102.0
ATP 132.0 406
Cdh 151.0 134.4
Fmd/Fwd 57.4 6.4
Fpo 27.8 3.96
Ftr 9.60 4.72
HdrDE 45.3 38.1
Mch 30.0 11.6
Mcr 321.8 398
Mer 25.5 1.26
MtaCBA1 1.97a 3.57
MtaCBA2 10.78 5.66
MtaCBA3 0.20a 141.0
Mtd 36.9 1.69
Mtr 112.4 144.4
Pta 36.2 171.0
Rnf 22.8 17.1

Expression values of MtaCBA1 and MtaCBA3 were adjusted such that their ratios to MtaCBA2 were in agreement with the protein expression values measured experimentally [30].