Table 1: Islet autoantigens in type 1 diabetes.

AutoantigenAutoantibody Present before clinical onset

InsulinInsulin autoantibodiesIAA+
ProinsulinProinsulin autoantibodiesPAA?
Glutamic acid decarboxylase, 65 kDGAD65A+
Insulinoma antigen-2IA-2A+
ZnT8 transporterZnT8A+