Review Article

Origin and Regenerative Potential of Vertebrate Mechanoreceptor-Associated Stem Cells

Figure 1

Anatomical localization of Meissner corpuscles (MCs) and Merkel cell-neurite complexes (MCN) within rodent hard palate. (a) MCs are located centrally within palatal rugae in the lamina propria, whereas MCN can be found within the basal layer. (b) Nestin expression within rat palatal MCs and adjacent to MCN. Cryosections of rat hard palate were stained with mouse anti-Nestin antibody (clone Rat401) followed by incubation with secondary Alexa555-coupled anti-mouse detection antibody. Confocal analysis revealed strong immunoreactivity in numerous cells within MCs and adjacent to MCN.
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(a)
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(b)