Review Article

Preoperative Assessment of Adult Patients for Intracranial Surgery

Table 3

Differences between diabetes insipidus and syndrome of inappropriate antidiuretic hormone.

Diabetes insipidusSyndrome of inappropriate
antidiuretic hormone

PresentationPolyuria Thirst (awake patients)Hyponateriamia
Serum sodiumIncreased 145 mEq/LDecreased 135 mEq/L
Serum osmolarityHigh 310 mOsm/LLow/hypotonic 275 mOsm/L
Urine volumeIncreased volume 4 L/dayLow
TreatmentSupportive fluid replacement and DDAVPFluid restriction with hypertonic sodium correction if serum sodium 120 mEq/L