The Effect of Prophylactic Dexmedetomidine on Hemodynamic Disturbances to Double-Lumen Endotracheal Intubation: A Prospective, Randomized, Double-Blind, and Placebo-Controlled Trial

Table 1

Patient characteristics and operative data.

Variables	Dexmedetomidine group (𝑛=30)	Control group (𝑛=30)
Age (yr)	48.0±19.4	47.8±15.1
Sex
Female	12 (40)	17 (57)
Male	18 (60)	13 (43)
ASA
I	11 (37)	8 (27)
II-III	19 (63)	22 (73)
Body mass index (kg/m^2)	21.2±3.3	20.8±3.3
Concurrent disease
Hypertension	10 (33)	6 (20)
Diabetes mellitus	3 (10)	1 (3)
Duration of anesthesia (minutes)	172±80	154±68
Duration of surgery (minutes)	142.3±80.4	121.3±67.5
Type of operation
Thoracoscopy	11 (37)	18 (60)
Thoracotomy	19 (63)	12 (40)
Extent of surgery
Explorative thoracotomy	9 (31)	11 (39)
Wedge resection	5 (17)	6 (21)
Lobectomy	15 (52)	10 (36)
Pneumonectomy	0	1 (4)
Baseline hemodynamic variables
SBP (mmHg)	141.6±19.7	136.1±18.9
DBP (mmHg)	78.9±9.6	74.8±12.4
MAP (mmHg)	101.9±12.2	95.9±14.9
HR (beats per minute)	78.4±17.1	81.2±16.7
RPP (mmHg min^−1)	11,094.0±2,571.2	10,931.7±2,381.8
Intubation time (seconds)	19.8±6.9	20.7±8.7

Data are presented as mean ± SD or number (%).
ASA: The American Society of Anesthesiologists, SBP: systolic blood pressure, DBP: diastolic blood pressure, MAP: mean arterial pressure, HR: heart rate, RPP: rate pressure product.