Research Article

Comparison of the Effects of Target-Controlled Infusion of Propofol and Sevoflurane as Maintenance of Anesthesia on Hemodynamic Profile in Kidney Transplantation

Table 2

Patients’ perioperative data.

VariablesTCI propofol (n = 23)Sevoflurane (n = 23) value

Surgery duration (hour)>3-41 (4.3%)4 (17.4%)0.268
>4-513 (56.5%)13 (56.5%)
>5-69 (39.1%)4 (17.4%)
60 (0%)2 (8.7%)
Anesthesia duration (hour)>3-40 (0%)0 (0%)0.583
>4-51 (4.3%)1 (4.3%)
>5-69 (39.1%)11 (47.8%)
>613 (56.5%)11 (47.8%)
Sevoflurane concentration (MAC)0.7 (0.6–0.9)
Total propofol usage (mg/hour)1,200 (650–3,325)
Total blood loss (ml)75.0 (50–150)100 (50–200)0.134
Total intraoperative fluid (ml)500 (150–1,000)700 (400–1,000)0.334
Minimum norepinephrine dosage (mcg/kg/min)0.02 (0.01–0.05)0.01 (0.01–0.05)0.191
Maximum norepinephrine dosage (mcg/kg/min)0.15 (0.05–0.5)0.1 (0.05–0.4)0.550
Minimum dobutamine dosage (mcg/kg/min)0.1 (0.1–1)0.1 (0.1–3)0.079
Maximum dobutamine dosage (mcg/kg/min)5 (0–5)10 (0–10)0.031
Intraoperative fentanyl usage (mcg/kg/hour)1.1 ± 0.51.0 ± 0.40.490
Urine output postreperfusion (ml/hour)382.6 ± 215.4410.21 ± 346.880.817

Data are presented as total (%) or as geometric mean and confidence interval 95% (minimum-maximum), is significant. Data are analyzed with chi-square, unpaired t-test, or Mann–Whitney. TCI, target-controlled infusion.