Impact of Melatonin as a Premedication Agent in Caesarean Section on Blood Loss and Postoperative Pain Level

Table 3

Comparison of visual pain scores.

Pain score	Melatonin, n = 40	Placebo, n = 40	Test ()
During cannula
Median (range)	2.0 (1.0–5.0)	3.0 (1.0–8.0)	U = 1276.0,
IQR (25–75)	2.0–3.0	3.0–5.0
During spinal needle
Median (range)	3.0 (2.0–5.0)	5.50 (3.0–10.0)	U = 1372.0,
IQR (25–75)	2.0–4.0	3.50–7.0
Post 30 min
Median (range)	1.0 (0.0–2.0)	0.0 (0.0–4.0)	U = 428.0,
IQR (25–75)	0.0–1.0	0.0–0.0
Post 1 h
Median (range)	0.0 (0.0–2.0)	1.0 (0.0–2.0)	U = 978.0,  = 0.063
IQR (25–75)	0.0–1.0	0.0–2.0
Post 2 h
Median (range)	1.0 (0.0–4.0)	2.0 (1.0–3.0)	U = 1000.0,  = 0.036
IQR (25–75)	1.0–2.0	1.0–2.0
Post 3 h
Median (range)	2.0 (1.0–4.0)	4.0 (1.0–6.0)	U = 1280.5,
IQR (25–75)	2.0–3.0	3.0–4.0

Range, min–max; U, Mann–Whitney; value compared between melatonin and placebo; significant when value <0.05.