Impact of Melatonin as a Premedication Agent in Caesarean Section on Blood Loss and Postoperative Pain Level

Table 4

Comparison of postoperative opioid administration.

Postoperative opioid administration	Melatonin, n = 40		Placebo, n = 40		Test ()
	No.	%	No.	%
After 1 hour
No	38	95.0	33	82.5	x^2 = 3.130, Fisher exact  = 0.154
Yes	2	5.0	7	17.5
After 2 hours
No	36	90.0	32	80.0	x^2 = 1.569,  = 0.210
Yes	4	10.0	8	20.0
After 3 hours
No	29	72.5	17	42.5	x^2 = 7.366,  = 0.007
Yes	11	27.5	23	57.5

x², chi-square test; value compared between melatonin and placebo; significant when value <0.05.