Clinical Study

Time to and Predictors of CD4+ T-Lymphocytes Recovery in HIV-Infected Children Initiating Highly Active Antiretroviral Therapy in Ghana

Table 4

Adjusted associations of patient characteristics and time to CD4+ T-lymphocyte recovery in 233 HIV-infected children on highly active antiretroviral therapy (HAART) from 2004–2009, Accra, Ghana.

Predictors Hazard ratio (95% CL) 𝑃 -value

Parental living status.025
 Both parents alive1.98 (1.18, 3.35)
 One parent known to be alive2.00 (1.18, 3.38)
 Both parents dead or unknown1.00
Gender.051
 Female1.37 (1.00, 1.87)
 Male1.00
Age category.014
 <12 months0.98 (0.44, 2.20)
 1–5 years1.59 (1.15, 2.19)
 >6 years1.00
 <12 months*0.62 (0.28, 1.37)
 1–5 years1.00
WHO immune classification<.0001
 No evidence of suppression2.31 (1.48, 3.63)
 Evidence of moderate suppression2.04 (1.46, 2.86)
 Severe suppression1.00

*Small sample size in children <12 months.