Assessing the Association between Leptin and Bone Mineral Density in HIV-Infected Men

Table 2

Multivariate regression models.

Primary predictor	Total BMD		Total BMC
	Std Reg Coeff^# (95% CI)	𝑃-value	Std Reg Coeff^# (95% CI)	𝑃-value
All subjects (𝑛=107)
Leptin (ln)^*	0.08 (−0.11, 0.27)	0.38	0.06 (−0.13, +0.25)	0.54
Leptin (ln)^**	−0.11 (−0.34, +0.12)	0.35	−0.19 (−0.38, +0.01)	0.07
Subjects with lipoatrophy (𝑛=33)
Leptin (ln)^*	−0.68 (−1.22, −0.14)	0.02	−0.74 (−1.27, −0.21)	<0.01
Leptin (ln)^&	−0.92 (−1.62, −0.22)	0.01	−0.80 (−1.32, −0.29)	<0.01

^#Standardized regression coefficient.
^*Adjusted for age and race.
^**Adjusted for age, race, truncal fat, appendicular fat, and lean body mass.
^&Adjusted for age, race, lean body mass, truncal fat, and total fat.