Clinical Study

Differences in Lipid Measurements by Antiretroviral Regimen Exposure in Cohorts from Asia and Australia

Table 2

Number and frequency of total cholesterol measurements by type of regimen and cohort.

cART RegimenAHOD No. of patients*AHOD median (range) no. of measurements per patientAHOD no. (%) of measurementsTAHOD no. of patients*TAHOD median (range) no. of measurements per patientTAHOD no. (%) of measurements

NRTIs (+TDF) + NVP1222 (1–6)247 (10.8)701 (1–4)108 (1.9)
NRTIs (+TDF) + EFV1312 (1–4)245 (10.7)901 (1–4)147 (2.6)
NRTIs + NVP1552 (1–6)342 (14.9)6961 (1–8)1157 (20.6)
NRTIs + EFV972 (1–4)211 (9.2)6842 (1–10)1487 (26.5)
NRTIs (+TDF) + PI (+ATV)1401 (1–5)266 (11.6)201 (1–4)28 (0.5)
NRTIs (+TDF) + PI1872 (1–7)410 (17.9)1373 (1–6)367 (6.5)
NRTIs + PI (+ATV)782 (1–5)178 (7.7)2323 (1–6)610 (10.9)
NRTIs + PI1842 (1–6)396 (17.2)6203 (1–12)1698 (30.3)

Total10942295 (100)25485602 (100)

*Each patient could contribute to more than one regimen. AHOD: Australian HIV Observational Database; ATV: Atazanavir; EFV: Efavirenz; NNRTI: non- nucleoside reverse transcriptase inhibitors; NRTIs: nucleoside reverse transcriptase inhibitors; NVP: nevirapine; PI: protease inhibitor; TAHOD: TREAT Asia HIV Observational Database; TDF: tenofovir. Key. NRTIs are TDF based (NRTIs + TDF) or not (NRTIs) and PI as ATV based (PI + ATV) or not (PI).