Reduced Central Memory CD4+ T Cells and Increased T-Cell Activation Characterise Treatment-Naive Patients Newly Diagnosed at Late Stage of HIV Infection
Table 6
Multivariate logistic regression analysis of the association of demographic and HIV-related characteristic with AIDS presentation.
AIDS presentation (AIDS-defining condition at,
P
or within one month after, HIV diagnosis)
AOR
95% CI
(a) Patient factors
Age, years
1.015
0.982–1.050
0.374
Gender°
0.001
Male
9.369
2.401–36.551
Female
reference
Risk group°
Heterosexual
4.555
1.937–10.711
0.001
Other
reference
(b) T-cells immune phenotypes
CD4+ T cells/L % (each unit more)
0.996
0.993–0.998
0.002
CD8+ T cells/L % (each unit more)
0.977
0.931–1.026
0.356
CD4+CD127+ cells/L % (each unit more)
0.963
0.891–1.042
0.349
CD8+CD95+ cells/L % (each unit more)
0.994
0.874–1.130
0.922
CD8+CD38+ cells/L % (each unit more)
1.049
1.004–1.096
0.033
CD8+CD38+CD45R0+ cells/L % (each unit more)
1.002
0.956–1.052
0.923
AOR: adjusted odds ratio; 95% CI, 95% confidence interval. was considered to denote statistical significance. Other: homosexual, intravenous drug users, and other risks groups.
