Imputation of the Date of HIV Seroconversion in a Cohort of Seroprevalent Subjects: Implications for Analysis of Late HIV Diagnosis
Table 3
Years between the imputed date of seroconversion and the date of HIV diagnosis. Results in the subcohort of new diagnoses ().
Years between imputed date of seroconversion and date of HIV diagnosis
N
% DD*
Median (P25–P75)
Mean
Sex
<0.001
Men
2287
51.8
3.42 (1.65–5.83)
4.07
Women
641
50.2
2.77 (1.32–5.04)
3.51
Age at HIV diagnosis
<0.001
Up to 20
93
33.3
1.94 (1.08–3.05)
2.15
21–30
871
39.6
2.76 (1.33–5.01)
3.46
31–40
1133
52.0
3.36 (1.62–5.89)
4.09
41–50
549
61.9
3.83 (1.87–6.18)
4.38
51–60
209
69.9
4.22 (2.25–6.42)
4.60
Over 60
72
75.0
4.37 (2.29–6.47)
4.63
Not available
1
100.0
5.25 (5.25–5.25)
5.25
—
Transmission category
0.111
Injection drug user
296
66.6
3.86 (1.93–6.11)
4.34
Men who have sex with men
1339
41.3
2.97 (1.42–5.43)
3.77
Heterosexual risk exposure
1187
58.0
3.39 (1.62–5.79)
4.00
Other (vertical, transfusions, tattoos, etc.)
46
63.0
3.71 (2.02–5.94)
4.18
Don’t know/No answer
60
63.3
4.18 (2.12–6.44)
4.57
Educational level
0.640
No education or less than primary
187
63.1
3.62 (1.77–5.85)
4.06
Primary
928
57.0
3.40 (1.62–5.82)
4.05
Secondary completed
853
46.0
3.13 (1.48–5.57)
3.85
University completed
443
41.3
3.07 (1.48–5.55)
3.85
Not available
517
54.9
3.30 (1.61–5.61)
3.96
—
Country of origin
0.410
Spain
1958
49.4
3.14 (1.49–5.58)
3.87
Western Europe
82
50.0
3.47 (1.77–5.80)
4.19
Eastern Europe and Russia
64
51.6
3.15 (1.59–5.33)
3.74
Sub-Saharan Africa
215
61.9
3.73 (1.82–6.05)
4.21
North Africa
56
60.7
4.09 (1.88–6.49)
4.62
Latin America
522
54.8
3.43 (1.70–5.81)
4.04
Other/not available
31
38.7
3.09 (1.52–5.73)
3.97
All
2928
51.4
3.26 (1.56–5.68)
3.94
*DD: Delayed diagnosis (patients with CD4 count <350 cells/mm3 in the first year after HIV diagnosis or with AIDS-defining disease in the the first three months after HIV diagnosis).
