Clinical Study
Oral HIV-Associated Kaposi Sarcoma: A Clinical Study from the Ga-Rankuwa Area, South Africa
Table 1
Clinical and laboratory features of the patients at the time of oral HIV-KS diagnosis.
| | Males | Females | Total |
| Number of patients (%) | 17 (46%) | 20 (54%) | 37 (100%) | Age (years) | | | | Mean | 34 | 33 | 33.4 | Range | 11–55 | 19–46 | 11–55 | Standard deviation | 12.53 | 7.69 | 10.08 | Tobacco usage (%) | 7 (41%) | 2 (10%) | 9 (24%) | Number of patients in whom the initial presentation of HIV-KS was in the mouth | 8 (47%) | 13 (65%) | 21 (57%) | Number of patients in whom the initial presentation of HIV-KS was concurrently in the mouth and skin | 3 (18%) | 3 (15%) | 6 (16%) | Number of patients who developed cutaneous HIV-KS before oral HIV-KS diagnosis | 6 (35%) | 4 (20%) | 10 (27%) | Other oral lesions present | | | | Pseudomembranous candidiasis | 7 (41%) | 5 (25%) | 12 (34%) | Hairy leukoplakia | | 1 (5%) | 1 (2%) | Necrotizing gingivitis | 1 (6%) | | 1 (2%) |
| Total number of patients | 8 (47%) | 6 (30%) | 14 (38%) |
| Average CD4+ T-cell count at KS diagnosis (data available for 33 patients) [cells/mm3] | 141 | 85 | 107 | Range | 12–409 | 13–261 | 12–409 | Standard deviation | 117.40 | 77.99 | 106.99 | Number of patients diagnosed with HIV infection and oral KS at the same time | 10 (59%) | 7 (35%) | 17 (46%) | Number of patients who were diagnosed with HIV infection before the diagnosis of oral KS | 7 (41%) | 13 (65%) | 20 (54%) | Number of patients with single oral HIV-KS lesions | 5 (29%) | 3 (15%) | 8 (22%) | Number of patients with multiple oral HIV-KS lesions | 12 (71%) | 17 (85%) | 29 (78%) | Lesion phenotype | | | | Number of macular lesions | 9 (20%) | 8 (17%) | 17 (18%) | Number of papular lesions | 10 (22%) | 11 (23%) | 21 (23%) | Number of nodular lesions | 16 (36%) | 17 (35%) | 33 (35%) | Number of exophytic lesions | 10 (22%) | 12 (25%) | 22 (24%) |
| Total number of lesions | 45 (100%) | 48 (100%) | 93 (100%) |
| Lesion size | | | | Number of lesions <10 mm | 15 (33%) | 5 (10%) | 20 (22%) | Number of lesions ≥10 mm ≤50 mm | 25 (56%) | 40 (83%) | 65 (70%) | Number of lesions >50 mm | 5 (11%) | 3 (7%) | 8 (8%) |
| Total number of lesions | 45 (100%) | 48 (100%) | 93 (100%) |
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