Effects of Angiotensin Converting Enzyme Inhibitors on Liver Fibrosis in HIV and Hepatitis C Coinfection

Table 4

Number of subjects from each group with scores predictive of significant fibrosis at one year and three years (univariate analysis).

Indices	Control group	ACE-I/ARB group	Odds ratio (95% confidence interval)*	P value
APRI score > 1.5 at one year (%)	28 (23)	10 (30)	0.76 (0.41–1.40)	0.39
APRI score > 1.5 at three years (%)	31 (24)	7 (30)	0.77 (0.39–1.54)	0.48
FIB4 score > 3.25 at one year (%)	43 (35)	16 (49)	0.73 (0.48–1.11)	0.17
FIB4 score > 3.25 at three years (%)	48 (36)	11 (48)	0.76 (0.47–1.23)	0.30
Forns score > 6.9 at one year (%)	25 (50)	14 (74)	0.68 (0.46–1.00)	0.08
Forns score > 6.9 at three years (%)	27 (47)	12 (100)	0.47 (0.36–0.62)	<0.001

^*Odds ratio for an elevated score in the control group compared to the ACE-I/ARB group.