Did Universal Access to ARVT in Mexico Impact Suboptimal Antiretroviral Prescriptions?

Table 3

Reasons for therapy change by subsystem and period of analysis.

%	Until 2000				After 2001
	IMSS	SSA	INS	𝑃 value^a	IMSS	SSA	INS	𝑃 value
Total changes	133	6	404		476	148	547
Optimizing a previous suboptimal regimen	45.1	16.7	39.1	0.22	44.5	54.0	44.4	0.09
Presumed viral failure	33.8	50	35.9	0.67	31.9	24.3	36.9	0.01
Toxicity	12.8	16.7	21	0.03	14.1	9.4	14.8	0.11
Deemed inadequate	8.3	16.7	3.9	0.04	9.4	12.2	3.8	0.00
𝑃-value^b	0.04				0.00

aUntil 2000, the SSA was not included in comparisons for each reason due to the sample size.
^bThe distribution of reasons for change between facilities in each period is significantly different.