Research Article

Resistance to Cotrimoxazole and Other Antimicrobials among Isolates from HIV/AIDS and Non-HIV/AIDS Patients at Bugando Medical Centre, Mwanza, Tanzania

Table 5

Predictors of ESBL producing isolates among 155 clinical isolates.

ESBL nonproducer ESBL producerCrude
%% OR (95% CI)

Cotrimoxazole
 Resistant83 (69.8)35 (97.2) 0.0011
 Susceptible36 (30.2) 1 (2.8)15 (1.85–125 .5)
Amoxycillin-clavulanic
 Resistant 35 (31.3)35 (100)<0.001NA
 Susceptible 77 (68.7) 0. (0.0)
Ciprofloxacin
 Resistant14 (12.9)22 (75.9)<0.0011
 Susceptible95 (87.1) 7 (24.1)0.05 (0.01–0.13)
Ampicillin
 Resistant71 (72.5)29 (100)0.001NA
 Susceptible27 (27.5)0 (0.0)
Tetracycline
 Resistant47 (73.4)30 (100)0.002NA
 Susceptible17 (26.6) 0 (0.0)
Ceftriaxone
 Resistant19 (47.5)15 (83.3) 0.011
 Susceptible21 (52.5) 3 (16.7)5.52 (1.26–24.4)
HIV status
 Negative64 (53.8)19 (52.8)0.921
 Positive55 (46.2) 17 (47.2)1.04 (0.49–2.19)
Cotrimoxazole prophylaxis
 No23 (41.9) 5 (29.4)0.361
 Yes32 (58.1)12 (70.6)1.72 (0.53–5.57)