Predictors of Mortality among Adult Antiretroviral Therapy Users in Southeastern Ethiopia: Retrospective Cohort Study
Table 3
Cox regression model: Selected sociodemographic and clinical factors associated with mortality of ART clients in Goba Hospital, Southeast Ethiopia, 2013.
Variables
Death as an outcome
Unadjusted HR (95% CI)
Adjusted HR (95% CI)
Sex of participants
Male
3.60 (2.40–5.30)*
2.67 (1.74–4.10)**
Female
1.0
1
Educational level
No formal education
1.0
1.0
Primary
0.34 (0.13–0.84)*
0.28 (0.11–0.70)**
Secondary
0.65 (0.31–1.39)
0.34 (0.15–0.73)**
Tertiary
1.53 (0.77–3.05)
0.71 (0.34–1.46)
Functional status
Working
1.0
Ambulatory
1.11 (0.41–3.05)
1.62 (0.55–4.75)
Bedridden
4.99 (1.80–13.88)*
4.38 (1.55–12.36)**
Baseline WHO stage
WHO stage 1
0.17 (0.09–0.33)*
0.16 (0.08–0.33)**
WHO stage 2
0.22 (0.11–0.44)*
0.34 (0.16–0.73)**
WHO stage 3
0.30 (0.18–0.49)*
0.24 (0.13–0.43)**
WHO stage 4
1.0
Baseline CD4 count
≤200
2.5 (0.3–17.6)
201–300
0.3 (0.03–3.20)
—
>300
1.0
TB coinfection
Positive
4.7 (3.2–6.8)*
4.51 (2.86–7.11)**
Negative
1.0
1
Anemia status
Anemic
0.25 (0.04–1.52)
—
Nonanemic
1.0
Baseline BMI (kg/m2)
<18.5
1.83 (1.20–2.77)*
1.20 (0.77–1.87)
18.5–24.99
1.0
≥25.0
3.19 (1.61–6.36)*
3.71 (1.81–7.59)**
Opportunistic infection
Yes
6.27 (4.12–9.54)*
2.51 (1.46–4.31)**
No
1.0
Age group
15–30 years
1.47 (0.88–2.45)
31–40 years
0.84 (0.49–1.42)
—
≥41 years
1.0
HR: hazard ratio; *statistically significant at at the unadjusted HR model; **statistically significant at at the adjusted HR model (both 2 tailed).