Table 1: Characteristics of study subjects.
Mean ± SDRange
Age (years) 6 6 . 4 ± 8 . 2 50–88
Height (m) 1 . 5 6 ± 0 . 0 5 1.47–1.65
Body weight (kg) 5 8 . 4 ± 8 . 2 44–80
Body mass index (kg/m2) 2 4 . 1 ± 3 . 4 16.9–33.3
Lumbar spine BMD (g/cm2) 0 . 8 6 4 ± 0 . 2 0 4 0.524–1.316
Whole body BMD (g/cm2) 0 . 8 6 6 ± 0 . 1 0 8 0.647–1.109
Lean body mass (g) 3 4 2 2 9 ± 7 5 4 8 20720–64203
Total fat mass (g) 2 4 7 3 4 ± 6 1 3 5 14302–41201
Total fat percent (%) 4 0 . 8 ± 5 . 3 29.7–51.5
Serum BAP (U/L) 2 8 . 1 ± 9 . 8 11.7–49.8
Serum OC (ng/mL) 5 . 7 ± 2 . 2 1.7–11.9
Urinary pyridinoline (pmol/μmol Cr) 3 2 . 5 ± 9 . 3 19.3–63.6
Urinary deoxypyridinoline (nmol/mmol Cr) 6 . 5 ± 2 . 0 2.8–10.1
Urinary NTX (nmol BCE/mmol Cr) 5 7 . 9 ± 2 1 . 4 8.2–95.7
Serum leptin (ng/mL) 9 . 7 ± 4 . 7 1.8–21.1
Radiographic grade 2 . 4 7 ± 1 . 0 0 1–4
BMD: bone mineral density, BAP: bone-specific alkaline phosphatase, OC: osteocalcin, NTX: cross-linked N-terminal telopeptides of type I collagen, BCE: bone collagen equivalent, Cr: creatinine.
Normal ranges of urinary pyridinoline, deoxypyridinoline, and NTX were 17.7–41.9 pmol/μmol Cr and 2.8–7.6 nmol/mmol Cr, and 9.3–54.3 nM BCE/mM Cr, respectively. Normal ranges of serum BAP, OC, and leptin were 7.9–20.9 U/L, 3.1–12.7 ng/mL, and 2.5–21.8 ng/mL, respectively.