Table 1: Frequency of system involvement in childhood cPAN ( ).

StudyTotal Skin involvement (Subcutaneous nodules, livido reticularis, purpura, edema, and/or ulcers)Joint involvement (Arthralgia, arthritis)Muscle involvement (Myalgias, myositis)Nerve involvement (Mononeuritis multiplex, peripheral neuropathy, cranial nerve palsy, and/or abnormal nerve conduction)

Ozen et al. [4] 33 (100%)13 (39%)5 (15%)1 (3%)
Kumar et al. [5] 9 (100%)7 (78%)0 (0%)0 (0%)
Diaz-Perez et al. [6] 5 (100%)3 (60%)5 (100%)3 (60%)
Fink [7] 5 (100%)5 (100%)5 (100%)0 (0%)
Tinaztepe et al. [8] 4 (100%)4 (100%)4 (100%)0 (0%)
Sheth et al. [9] 4 (100%)4 (100%)4 (100%)2 (50%)
Topaloglu et al. [10] 3 (75%)2 (50%)3 (75%)4 (100%)
Fathalla et al. [11] 4 (100%)3 (75%)0 (0%)0 (0%)
Kirkali et al. [12] 2 (67%)0 (0%)1 (33%)3 (100%)
Yonis [13] 3 (100%)0 (0%)3 (100%)2 (67%)
Siberry et al. [14] 2 (100%)2 (100%)0 (0%)0 (0%)
Finkel et al. [15] 2 (100%)2 (100%)2 (100%)1 (50%)
Eleftheriou et al. [3] 2 (100%)0 (0%)1 (50%)1 (50%)
Till et al. [16] 2 (100%)2 (100%)0 (0%)0 (0%)
Single case reports [1753] (95%) (59%) (49%) (14%)

TOTAL 115 (96.6)69 (58.0)51 (42.9)22 (18.5%)