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Arthritis
Volume 2010 (2010), Article ID 924518, 4 pages
http://dx.doi.org/10.1155/2010/924518
Clinical Study

Staphylococcus aureus Decolonization Protocol Decreases Surgical Site Infections for Total Joint Replacement

NYU-Hospital for Joint Diseases, 301 East 17th Street New York, NY 10003, USA

Received 14 August 2010; Revised 22 October 2010; Accepted 3 November 2010

Academic Editor: Burkhard Leeb

Copyright © 2010 Scott Hadley et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. P. V. Giannoudis, J. Parker, and M. H. Wilcox, “Methicillin-resistant Staphylococcus aureus in trauma and orthopaedic practice,” Journal of Bone and Joint Surgery B, vol. 87, no. 6, pp. 749–754, 2005. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  2. K. B. Kirkland, J. P. Briggs, S. L. Trivette, W. E. Wilkinson, and D. J. Sexton, “The impact of surgical-site infections in the 1990s: attributable mortality, excess length of hospitalization, and extra costs,” Infection Control and Hospital Epidemiology, vol. 20, no. 11, pp. 725–730, 1999. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  3. T. M. Perl, J. J. Cullen, and J. J. Cullen, “Intranasal mupirocin to prevent postoperative Staphylococcus aureus infections,” New England Journal of Medicine, vol. 346, no. 24, pp. 1871–1877, 2002. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  4. W. Zimmerli, A. Trampuz, and P. E. Ochsner, “Current concepts: prosthetic-joint infections,” New England Journal of Medicine, vol. 351, no. 16, pp. 1645–1654, 2004. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  5. M. S. Favero, R. P. Gaynes, and R. P. Gaynes, “National Nosocomial Infections Surveillance (NNIS) report, data summary from October 1986-April 1996, issued May 1996. A report from the National Nosocomial Infections Surveillance (NNIS) System,” American Journal of Infection Control, vol. 24, no. 5, pp. 380–388, 1996. View at Publisher · View at Google Scholar · View at Scopus
  6. A. J. Mangram, T. C. Horan, M. L. Pearson, L. C. Silver, and W. R. Jarvis, “GGuideline for prevention of surgical site infection, 1999. Centers for Disease Control and Prevention (CDC) Hospital Infection Control Practices Advisory Committee,” American Journal of Infection Control, vol. 27, no. 2, pp. 96–97, 1999. View at Scopus
  7. T. C. Horan, M. Andrus, and M. A. Dudeck, “CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting,” American Journal of Infection Control, vol. 36, no. 5, pp. 309–332, 2008. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  8. M. C. Maranan, B. Moreira, S. Boyle-Vavra, and R. S. Daum, “Antimicrobial resistance in staphylococci. Epidemiology, molecular mechanisms, and clinical relevance,” Infectious Disease Clinics of North America, vol. 11, no. 4, pp. 813–849, 1997. View at Publisher · View at Google Scholar · View at Scopus
  9. R. P. Wenzel and T. M. Perl, “The significance of nasal carriage of Staphylococcus aureus and the incidence of postoperative wound infection,” Journal of Hospital Infection, vol. 31, no. 1, pp. 13–24, 1995. View at Publisher · View at Google Scholar · View at Scopus
  10. R. Schwarzkopf, R. C. Takemoto, I. Immerman, J. D. Slover, and J. A. Bosco, “Prevalence of Staphylococcus aureus colonization in orthopaedic surgeons and their patients: a prospective cohort controlled study,” The Journal of Bone and Joint Surgery, vol. 92, no. 9, pp. 1815–1819, 2010. View at Publisher · View at Google Scholar · View at PubMed
  11. M. D. Kalmeijer, H. Coertjens, and H. Coertjens, “Surgical site infections in orthopedic surgery: the effect of mupirocin nasal ointment in a double-blind, randomized, placebo-controlled study,” Clinical Infectious Diseases, vol. 35, no. 4, pp. 353–358, 2002. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  12. L. G. M. Bode, J. A. J. W. Kluytmans, and J. A. J. W. Kluytmans, “Preventing surgical-site infections in nasal carriers of Staphylococcus aureus,” New England Journal of Medicine, vol. 362, no. 1, pp. 9–17, 2010. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  13. J. C. De Lucas-Villarrubia, M. Lopez-Franco, J. J. Granizo, J. C. De Lucas-Garcia, and E. Gomez-Barrena, “Strategy to control methicillin-resistant Staphylococcus aureus post-operative infection in orthopaedic surgery,” International Orthopaedics, vol. 28, no. 1, pp. 16–20, 2004. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  14. M. D. Kalmeijer, “Nasal carriage of staphylococcus aureus is a major risk factor for surgical-site infections in orthopedic surgery,” Infection Control and Hospital Epidemiology, vol. 21, no. 5, pp. 319–323, 2000. View at Scopus
  15. D. T. M. Fascia, A. Singanayagam, and J. F. Keating, “Methicillin-resistant staphylococcus aureus in orthopaedic trauma: identification of risk factors as a strategy for control of infection,” Journal of Bone and Joint Surgery B, vol. 91, no. 2, pp. 249–252, 2009. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  16. C. C. Tai, A. A. Nirvani, A. Holmes, and S. P. F. Hughes, “Methicillin-resistant Staphylococcus aureus in orthopaedic surgery,” International Orthopaedics, vol. 28, no. 1, pp. 32–35, 2004. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  17. M. H. Wilcox, J. Hall, H. Pike, P. A. Templeton, W. N. Fawley, P. Parnell, and P. Verity, “Use of perioperative mupirocin to prevent methicillin-resistant Staphylococcus aureus (MRSA) orthopaedic surgical site infections,” Journal of Hospital Infection, vol. 54, no. 3, pp. 196–201, 2003. View at Publisher · View at Google Scholar · View at Scopus
  18. D. M. Hacek, W. J. Robb, S. M. Paule, J. C. Kudrna, V. P. Stamos, and L. R. Peterson, “Staphylococcus aureus nasal decolonization in joint replacement surgery reduces infection,” Clinical Orthopaedics and Related Research, vol. 466, no. 6, pp. 1349–1355, 2008. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  19. R. O. Darouiche, “Treatment of infections associated with surgical implants,” New England Journal of Medicine, vol. 350, no. 14, pp. 1422–1429, 2004. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  20. T. F. Moyad, T. Thornhill, and D. Estok, “Evaluation and management of the infected total hip and knee,” Orthopedics, vol. 31, no. 6, pp. 581–588, 2008. View at Publisher · View at Google Scholar · View at Scopus
  21. J. Slover, J. P. Haas, M. Quirno, M. S. Phillips, and J. A. Bosco, “Cost-effectiveness of a Staphylococcus aureus screening and decolonization program for high-risk orthopedic patients,” Journal of Arthroplasty. In press. View at Publisher · View at Google Scholar · View at PubMed