Review Article

Quantitative Cartilage Imaging in Knee Osteoarthritis

Table 1

Morphological (metrics), statistical, and anatomical (region of interest) labels commonly used in cartilage morphology publications on the knee.

AbbreviationExplanationUnit

Morphological (metrics) label
VCvolume of the cartilage(mm3/mL)
tABtotal area of subchondral bone(cm2)
ACarea of cartilage surface(cm2)
cABarea of tAB covered by AC(cm2)
dAB%percent of tAB denuded (not covered by AC)(%)
VCtABvolume of the cartilage divided by tAB(mm)
ThCtABthickness of the cartilage over the entire tAB(mm)
ThCcABthickness of cartilage over cAB(mm)

dAB%percent of tAB denuded (not covered by AC)(%)
VCtABvolume of the cartilage divided by tAB(mm)
ThCtABthickness of the cartilage over the entire tAB(mm)
ThCcABthickness of cartilage over cAB(mm)

Statistical labels
Memean (i.e., thickness)
Maxmaximum (i.e., thickness)
Mavmaximal averaged, for example, mean of the top 1% values
Minminimum (i.e., thickness)
Mivminimum averaged, for example, mean of the lowest 1% values
SDstandard deviation (i.e., thickness)
CV%coefficient of variation (i.e., thickness)
c(Me, Mav)thickness measured from cartilage surface (AC) to bone interface (tAB)
b(Me, Mav)thickness measured from bone interface (tAB) to cartilage surface (AC)
a(Me, Mav)average of the two above (b, c)

Anatomical (region of interest) labels
Total cartilage plates
 PPatella
 MTMedial tibia
 LTLateral tibia
 FFemur
 TrFFemoral trochlea
 MFMedial femoral condyle
   cMFweight-bearing portion of MF
   pMFposterior portion of MF
 LFLateral femoral condyle
   cLFweight-bearing portion of LF
   pLFposterior portion of LF
 MFTCaggregate values for MT and cMF (MT + cMF)
 LFTCaggregate values for LT and cLF (LT + cLF)

Subregions (to be combined with above total plate labels, i.e., cMT or ccMF)
ccentral
eexternal
iinternal
aanterior
pposterior

For anatomical (region of interest) labels, also see Figures 1 and 2.