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Arthritis
Volume 2011 (2011), Article ID 578252, 8 pages
http://dx.doi.org/10.1155/2011/578252
Review Article

Dynamic Contrast Enhanced MRI Can Monitor the Very Early Inflammatory Treatment Response upon Intra-Articular Steroid Injection in the Knee Joint: A Case Report with Review of the Literature

1Department of Radiology, Frederiksberg Hospital, Nordrefasanvej 57, Frederiksberg Hospital 2000 Frederiksberg, Denmark
2Parker Institute, Frederiksbeg Hospital, 2000 Frederiksberg, Denmark
3Image Analysis Ltd, Leeds, BD17 7EZ, UK
4Department of Rheumatology, University of Genoa, 16126 Genoa, Italy
5Department of Rheumatology Hvidovre, Herlev Hospitals, 2730 Herlev, Denmark
6Rheumatology Division, Kennedy Institute, Imperial College, London, SW7 2AZ, UK

Received 22 September 2010; Revised 1 December 2010; Accepted 21 January 2011

Academic Editor: Pascal Richette

Copyright © 2011 Mikael Boesen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Dynamic contrast-enhanced MRI in inflammatory arthritis, especially in conjunction with computer-aided analysis using appropriate dedicated software, seems to be a highly sensitive tool for monitoring the early inflammatory treatment response in patients with rheumatoid arthritis. This paper gives a review of the current knowledge of the emerging technique. The potential of the technique is demonstrated and discussed in the context of a case report following the early effect of an intra-articular steroid injection in a patient with rheumatoid arthritis flare in the knee.