Serum Leptin Concentration Positively Correlates with Body Weight and Total Fat Mass in Postmenopausal Japanese Women with Osteoarthritis of the Knee

Table 2

Correlations of serum leptin level with various factors by simple regression analysis.

	Correlation coefficient	𝑃 value
Age (years)	−0.240	NS
Height (m)	0.162	NS
Body weight (kg)	0.792	<.0001
Body mass index (kg/m^2)	0.693	<.0001
Lumbar spine BMD (g/cm^2)	0.255	NS
Whole body BMD (g/cm^2)	0.440	.0014
Lean body mass (g)	0.189	NS
Total fat mass (g)	0.706	<.0001
Total fat percent (%)	0.511	<.0001
Serum BAP (U/L)	−0.085	NS
Serum bone Gla protein (ng/mL)	−0.267	NS
Urinary pyridinoline (pmol/μmol Cr)	0.138	NS
Urinary deoxypyridinoline (nmol/mmol Cr)	0.086	NS
Urinary NTX (nmol BCE/mmol Cr)	−0.151	NS
Radiographic grade	−0.110	NS

A simple linear regression analysis was used to examine correlations of serum leptin level with various factors. BMD: bone mineral density, BAP: bone-specific alkaline phosphatase, NTX: cross-linked N-terminal telopeptides of type I collagen, BCE: bone collagen equivalent, Cr: creatinine, NS: not significant.